Automatic leukocoria detection
This page is about our research on automatic detection of leukocoria (white-eye
reflection) using software. Our research is producing algorithms which can
learn from examples to automatically detect when a photo contains a white-eye
reflection that may be an indication of a solid-tumor pediatric cancer called
Retinoblastoma. Here is an example of an eye that appears leukocoric:
Our research involves analyzing images of eyes detected within larger natural
images. As such, we are especially interested in separating true leukocoria
(caused by diseases such as Retinoblastoma) from normal (black and red) pupils,
as well as pseudoleukocoria (caused by some camera flashes, but not indicating
a negative condition).
iPad / iPhone app
You can download our white-eye detector app from the Apple app store! Please give it a try.
We previously had a web-based version of this software available, but the app
version has much better software support. Please use that version.
- Detection of Leukocoria using a Soft Fusion of Expert Classifiers under Non-clinical Settings. Pablo Rivas-Perea, Erich Baker, Greg Hamerly, and Bryan Shaw. In BMC Opthamology, 2014.
- Finding the Smallest Circle Containing the Iris in the Denoised Wavelet Domain. Pablo Rivas-Perea, Ryan Henning, Bryan Shaw, and Greg Hamerly. In proceedings of SSIAI 2014. Here is the IEEE link.
- A Convolutional Neural Network Approach for Classifying Leukocoria. Ryan Henning, Pablo Rivas-Perea, Bryan Shaw, and Greg Hamerly. In proceedings of SSIAI 2014. See attributions for Flickr data used in our study. Here is the IEEE link.
- Colorimetric and Longitudinal Analysis of Leukocoria in Recreational Photographs of Children with Retinoblastoma.
Alireza Abdolvahabi, Brandon W. Taylor, Rebecca L. Holden, Elizabeth V. Shaw, Alex Kentsis, Carlos Rodriguez-Galindo, Shizuo Mukai, and Bryan F. Shaw. PLOS One, October 30 2013.
- Deutschland RTL Now — fast-forward to 20:50 (RTL.de, November 26 2014)
- Neue App kann Kinderleben retten! (Bild, November 24 2014)
- Eye disease catching app for iphone could save vision and lives (TMR, November 15 2014)
- White Eye app can give red flag to eye abnormalities (BBC, November 12 2014)
- App Helps Detect Cancer Hiding in Plain Sight (CBS Austin, November 6 2014)
- App made to detect possible eye disease (Baylor Lariat, November 6 2014)
- Eye cancer in children? Baylor profs develop an app for that (Waco Tribune-Herald, November 2 2014)
- Look Here: Phone App Checks Photos For Eye Disease (NPR, October 31 2014)
- White-Eye Photos May Indicate Rare Cancer In Children (CBS Dallas/Fort Worth, May 19 2014)
- Faith Drives A Father To Create A Test For Childhood Cancer (NPR, May 7 2014)
- Chemist Turns Software Developer After Son's Cancer Diagnosis (NPR, May 6 2014)
- How Pictures Of Infant Boy's Eyes Helped Diagnose Cancer (NPR, November 6 2013)
Dr. Bryan Shaw on TEDxUtica (November 7, 2014)
- Dr. Greg Hamerly, associate professor in computer science, Baylor University
- Ryan Henning, MS computer science, Baylor University (Ryan has done most of the code for the iPhone / iPad app)
- Dr. Bryan Shaw, assistant professor in chemistry, Baylor University
- Dr. Pablo Rivas Perea, postdoctoral researcher in computer science, Baylor University
- Dr. Erich Baker, associate professor in bioinformatics, Baylor University
- Ryan Yan, MS student in computer science, Baylor University
- Li Guo, MS computer science, Baylor University
- Tak-Chien Chiam, MS computer science, Baylor University